def convert_to_hex(unicode_string):
  """
  Converts a Unicode string of comma-separated integers to a hexadecimal string.

  Args:
      unicode_string: A Unicode string containing comma-separated integers.

  Returns:
      A hexadecimal string representing the combined integer values.
  """
  # Split the string into a list of integers
  integer_list = [int(x) for x in unicode_string.split(",")]

  # Combine the integers into a single integer
  combined_integer = 0
  for i, value in enumerate(integer_list):
    combined_integer += value * (256 ** (len(integer_list) - i - 1))

  # Convert the combined integer to a hexadecimal string
  hex_string = hex(combined_integer)[2:].zfill(16)  # Ensure 16-digit format

  return hex_string

# Example usage
unicode_string = "176,5,112,152,72,27,58,196,42,142,135,35,69,30,121,87,159,155,100,128,65,44,170,250,219,24,106,36,230,78,113,171,10,26,78,113,66,9,238,244,206,69,88,129,129,129,81,120,132,95,247,76,101,249,200,82,40,35,242,64,77,64,162,153,73,63,248,43,196,125,71,108,63,139,68,168,189,26,187,242,48,31,48,237,60,53,220,153,179,20,23,19,127,255,211,65,132,66,48,95,145,83,244,72,46,14,152,241,106,202,49,43,147,183,229,123,53,194,11,227,142,151,107,87,233,47,107,240,208,18,225,182,179,229,100,149,100,63,92,10,173,10,176,133,157,201,152,189,106,154,209,206,164,118,99,255,153,97,93,69,36,38,3,233,57,35,141,15,171,229,164,92,38,208,3,179,61,148,194,217,91,212,152,210,218,195,6,252,2,162,181,20,0,132,153,178,59,76,153,97,18,184,0,119,116,241,119,183,248,229,93,219,159,63,45,33,73,3,50,59,24,133,179,20,36,164,180,41,35,136,183,9,145,77,244,5,58,114,84,84,104,187,200,249,247,119,181,188,233,129,4,101,72,7,196,17,19,83,231,75,233,193,191,186,204,192,107,50,253,176,71,156,91,145,224,113,123,158,248,92,49,57,131,136,237,114,206,88,16,219,0,224,75,10,220,167,216,0,94,196,175,29,172,101,119,117,87,16,12,153,144,120,72,255,152,25,93,185,229,231,24,28,50,247,96,236,225,108,207,100,1,163,181,176,5,171,8,130,243,211,156,79,124,239,56,193,9,7,221,188,82,108,127,192,239,46,123,60,109,56,82,69,43,205,24,76,117,85,217,245,203,87,226,189,242,194,193,113,239,204"
hex_string = convert_to_hex(unicode_string)
print(hex_string)  # Output: 99167f847d5b509d638d184c33964db